Publications

On this page, you can find a number of publications where CFIM equipment has been used. Please note that this is not a complete list of publications where CFIM microscopes have been used to process or produce images.

Acknowledgements

If you are publishing an article with results obtained with CFIM microscopes, please make sure to acknowledge CFIM: "We acknowledge the Core Facility for Integrated Microscopy, Faculty of Health and Medical Sciences, University of Copenhagen".

In addition, we would be grateful to receive a pdf version of the paper in which CFIM has been acknowledged. Thereby, your paper will also be published in the list below.

 

Schultz et al. in ACS Applied Materials & Interfaces
Gastrointestinal Device-Mediated Delivery of mRNA-Lipid Nanoparticles Achieves Distinct Expression and Biodistribution in Mice and Pigs

Göransson et al. in Breast Cancer Research
Low-dose tamoxifen treatment reduces collagen organisation indicative of tissue stiffness in the normal breast: results from the KARISMA randomised controlled trial

Atudorei et al. in Neurobiology of Disease
Bilateral chemogenetic activation of intratelencephalic neurons in motor cortex reduces spontaneous locomotor activity in mice

Norheim et al. in Nature Aging
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial

Sunnerhagen et al. in Biofilm
Transcatheter aortic valve implantation (TAVI) prostheses in vitro-biofilm formation and antibiotic effects

Kristensen et al. in Nature Metabolism
Skeletal muscle from TBC1D4 p. Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise

Sarusie et al. in Human Molecular Genetics
A novel GFAP frameshift variant identified in a family with optico-retinal dysplasia and vision impairment

Distefano et al. in Free Radic Biol Med
Harmonization of experimental procedures to assess mitochondrial respiration in human permeabilized skeletal muscle fibers

Mirian et al. in Journal of Proteome Research
Deep Proteome Analysis of Cerebrospinal Fluid from Pediatric Patients with Central Nervous System Cancer

Walker et al. in Communications Biology
Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

Juul et al. in Scientific Reports
Autologous micrografting improves regeneration of tissue-engineered urinary conduits in vivo

Sørensen et al. in KeAi
Bioactive Diamond Scaffolds Support Survival and Axonal Regeneration of Hesc-Derived Injured Interneurons

Nielsen et al. in Nature
Structure of the human dopamine transporter in complex with cocaine

Doerrier et al. in Free Radical Biology and Medicine
Harmonization of experimental procedures to assess mitochondrial respiration in human permeabilized skeletal muscle fibers

Luque-Fernández et al. in PNAS
An ankyrin G–binding motif mediates TRAAK periodic localization at axon initial segments of hippocampal pyramidal neurons

Achter et al. in Cardiovascular Diabetology
In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation

Agbaje in Microchemical Journal
Microscale analysis reveals nature of hydrophobic biopolymers in aragonite bivalve shells with crossed-lamellar architecture

Tenjo-Castaño et al. in Molecular Cell
Conformational landscape of the type VK CRISPR-associated transposon integration assembly

Carabias et al. in Molecular Cell
Retron-Eco1 assembles NAD+-hydrolyzing filaments that provide immunity against bacteriophages

Bagdonaite et al. in Journal of Virology
Targeting host O-linked glycan biosynthesis affects Ebola virus replication efficiency and reveals differential GalNAc-T acceptor site preferences on the Ebola virus glycoprotein

Alsing et al. in Am J Case Rep
Unveiling the Temporal Aspect of MRI Tattoo Reactions: A Prospective Evaluation of a Newly-Acquired Tattoo with Multiple MRI Scans

Kvam et al. in BMC biology
High incidence of imperforate vagina in ADGRA3-deficient mice

Stie et al. in Sustainable Materials and Technologies
Sustainable strategies for waterborne electrospinning of biocompatible nanofibers based on soy protein isolate

Delle et al. in Fluids and Barriers of the CNS
Transient but not chronic hyperglycemia accelerates ocular glymphatic transport

Hendiani et al. in bioRvix
Reconciling the importance of minerals for propagation of antibiotic resistance genes in the environment

Ye et al. in Bio Protoc
Phosphoproteomic Analysis and Organotypic Cultures for the Study of Signaling Pathways

Cregg et al. in Nature Neuroscience
Basal ganglia–spinal cord pathway that commands locomotor gait asymmetries in mice

Nielsen et al. in Scand J Med Sci Sports
Assessments of individual fiber glycogen and mitochondrial volume percentages reveal a graded reduction in muscle
oxidative power during prolonged exhaustive exercise

Wohlsein et al. in PLoS ONE
Neutrophil extracellular traps in CSF and serum of dogs with steroid-responsive meningitis-arteritis

Lenton et al. in bioRxiv
Amyloid Morphology is Encoded in H-bonds and Electrostatics Interactions Ruling Protein Phase Separation

 

 

Xu et al. in Antimicrobial Chemotherapy
A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology

Sørensen et al. in microLife
Agtrevirus phage AV101 recognizes four different O-antigens infecting diverse E. coli

Røder et al. in Applied and Environmental Microbiology
Flagellar interference with plasmid uptake in biofilms: a joint experimental and modeling study

Kristensen et al. in Viruses
Co-localization of influenza A virus and voltage-dependent calcium channels provides new perspectives on the internalization process in pigs

Nguyen et al. in Nature Communications
Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome

Rognant et al. in the FASEB Journal
Acute, pro‐contractile effects of prorenin on rat mesenteric arteries

Skafte-Holm et al. in International Journal of Systematic and Evolutionary Microbiology
Mycoplasma phocimorsus sp. nov., isolated from Scandinavian patients with seal finger or septic arthritis after contact with seals

Walker et al. in Nature Portfolio
Novel, broad and potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

Couston et al. in Current Research in Structural Biology
Cryo-EM structure of the trehalose monomycolate transporter, MmpL3, reconstituted into peptidiscs

Lopez et al. in Cell Reports
Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence

Bagdonaite et al. in Nature Communications
Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 infection

Martinez et al. in Infection and Immunity
Development of a Tag/Catcher-mediated capsid virus-like particle vaccine presenting the conserved Neisseria gonorrhoeae SliC antigen that blocks human lysozyme

Knudsen et al. in American Journal of Physiology-Endocrinology and Metabolism
No Net-Utilization of Intramuscular Lipid Droplets during Repeated High-Intensity Intermittent Exercise

Mellergaard et al. in Immunology

Clinical Staphylococcus aureus inhibits human T-cell activity through interaction with the PD-1 receptor

Tresse et al. in Molecular Psychiatry
Mitochondrial DNA damage triggers spread of Parkinson’s disease-like pathology

Saenz et al. in Microbiology Spectrum
Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner

Leal-Dutra et al. in IMA Fungus
Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers

Grycel et al.in Mol Cell Neurosci
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum

Alsing et al. in Case Rep Dermatol
MRI-Induced Neurosensory Events in Decorative Black Tattoos: Study by Advanced Experimental Methods

Baadsgaard Bruun et al. in Veterinary Ophthalmology
The use of a “horizontal centrifugation protocol” to prepare autologous platelet-rich fibrin membranes for corneal reconstruction surgery in dogs with complicated corneal ulcerations: A case series

Bering et al. in Glia
Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus

Højfeldt et al. in Skeletal Muscle
Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration

Raghavan et al. in Structure
Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1

Henriquez-Olguin et al. in Redox Biology
NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle

Rusiecka et al. in Cardiovascular Research
Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

Clemen et al. in Redox Biology
Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells

Kido et al. in Diabetes
AMPKγ3 controls muscle glucose uptake in recovery from exercise to recapture energy stores.

Goñi-Erro et al. in Nature Neuroscience
Pedunculopontine Chx10+ neurons control global motor arrest in mice.

Hu et al. in Nature Communications
Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit

Dahl et al. in Clinical Neuroradiology
Fragmentation of Hydrophilic Guidewire Coatings During Neuroendovascular Therapy

 Xu et al. in Antimicrob Agents Chemother
A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology

Alobaidallah et al. in Antibiotics
Uncovering the Important Genetic Factors for Growth during Cefotaxime-Gentamicin Combination Treatment in blaCTX-M-1 Encoding Escherichia coli

Højfeldt et al. in Skeletal Muscle
Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration

Etich et al. in EMBO Molecular Medicine
TAPT1—at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta

Mahdi et al.
Targeting peptidylarginine deiminase reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis

Birch et al. in Pharmaceutics
Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin

Fradera-Soler et al. in Plant, Cell & Environment
Revisiting an ecophysiological oddity: hydathode-mediated foliar water uptake in Crassula species from southern Africa

Gundorff Nielsen et al. in the European Journal of Inorganic Chemistry
1-Azathioxanthone Appended Lanthanide(III) DO3A Complexes That Luminesce Following Excitation at 405 nm**

Sasnauskas et al. in Nature
TnpB structure reveals minimal functional core of Cas12 nuclease family

Daradoumis et al. in Viruses
An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice

Noes-Holt et al. in bioRxiv
Recombinant dimeric PDZ protein inhibitors for long-term relief of chronic pain by AAV therapeutics

Jensen et al. in bioRxiv
mPD5, an efficacious PICK1 inhibitor for treating chronic pain

Rømer et al. in Glycobiology
CRISPR-screen identifies ZIP9 and dysregulated Zn2+ homeostasis as a cause of cancer-associated changes in glycosylation.

Pedersen et al. in International Journal of Molecular Science
Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

Danielsen et al. in International Journal of Biological Macromolecules
Formulation and characterization of insulin nanoclusters for a controlled release

Wang et al. in Pharmaceutics
Drug Combination of Ciprofloxacin and Polymyxin B for the Treatment of Multidrug–Resistant Acinetobacter baumannii Infections: A Drug Pair Limiting the Development of Resistance

Hsu et al. in Nature Communications
Deconstructing the modular organization and real-time dynamics of mammalian spinal locomotor networks

Simón et al. in International Journal of Nanomedicine
Neoadjuvant Gold Nanoshell-Based Photothermal Therapy Combined with Liposomal Doxorubicin in a Mouse Model of Colorectal Cancer

Santos et al. in bioRxiv
Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability

Cai et al. in Nature Aging
Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

Taylor et al. in Research Square
Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit

Bjerregaard et al. in Genes
Involvement of Mitochondrial Dysfunction in FOXG1 Syndrome

Goksøyr et al. in Vaccines
A cVLP-Based Vaccine Displaying Full-Length PCSK9 Elicits a Higher Reduction in Plasma PCSK9 Than Similar Peptide-Based cVLP Vaccines

 

 

Ye et al. in Science Signaling
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

Pérez-Hernández et al. in Circulation
Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC

Møller et al. in Cell Tissue Research
An ultrastructural study of the deep pineal gland of the Sprague Dawley rat using transmission and serial block face scanning electron microscopy: cell types, barriers, and innervation

Vigh-Larsen et al. in The Journal of Physiology
Fibre type and localisation‐specific muscle glycogen utilisation during repeated high‐intensity intermittent exercise

Vigh-Larsen et al. in Medicine and Science in Sports and Exercise
The Role of Muscle Glycogen Content and Localization in High-Intensity Exercise Performance: A Placebo-Controlled Trial

Müllertz et al. in Molecular Pharmaceutics
Pulmonary Administration of the Liposome-Based Adjuvant CAF01: Effect of Surface Charge on Mucosal Adjuvant Function

Neopane et al. in Cell Reports
Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

Adams et al. in iScience
3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting
genospecies dependent organotropism

Zhang et al. in Nature Communications
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

Ibarra et al. in Research Square
Beta cell dysfunction and dedifferentiation induced by Bone Morphogenetic Protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

Kilic et al. in Proteomics
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

Kverneland et al. in Proteomics
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles

Raghavan et al. in PLOS Pathogens
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1. 4 broadly reacting with polymorphic malarial protein VAR2CSA

Schmidt in Studies in Conservation
Species Identification of Common Native Arctic Mammals in Inuit Fur Clothing Based on Hair Microscopy

Prentoe et al. in npj Vaccines
Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

Stie et al. in Sustainable Materials and Technologies
Sustainable strategies for waterborne electrospinning of biocompatible nanofibers based on soy protein isolate

Nielsen et al. in ChemRxiv
1-Azathioxanthone Appended Europium(III) Complexes with Excita-tion at 405 nm: Consequences for Lanthanide Luminescence based Bioimaging on Commercial Microscopes

Adamo et al. in The American Journal of Human Genetics
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis

Skamris et al. in Protein Aggregation
Identifying Biological and Biophysical Features of Different Maturation States of α-Synuclein Amyloid Fibrils

Thorlaksen et al. in Protein Aggregation
Reproducible Formation of Insulin Superstructures: Amyloid-Like Fibrils, Spherulites, and Particulates

Ventura et al. in Nature Communications
Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivo

Bor et al. in ACS Applied Materials & Interfaces
PEGylation of Phosphatidylglycerol/Docosahexaenoic Acid Hexosomes with d-α-Tocopheryl Succinate Poly(ethylene glycol)2000 Induces Morphological Transformation into Vesicles with Prolonged Circulation Times

Huang et al. in Macromolecules
Spatial Radical Distribution in Fractured Polymer Glasses and Melts Visualized Using a Profluorescent Nitroxide Probe

Thorlaksen et al. in European Journal of Pharmaceutics and Biopharmaceutics
Subtle pH variation around pH 4.0 affects aggregation kinetics and aggregate characteristics of recombinant human insulin

Zhu et al. in Microbiology Spectrum
Outer Membrane Vesicles of Actinobacillus pleuropneumoniae Exert Immunomodulatory Effects on Porcine Alveolar Macrophages

Rudjord-Levann et al. in Research Square
Galectin-1 upregulates IDO1 and PD-L1 and induces a tolerogenic tumor-associated macrophage phenotype

Ringholm et al. in The Journals of Gerontology
Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

Ozhathil et al. in In Vitro Cellular & Developmental Biology - Animal
Time matters: characterization of fibroblast-like cells harvested from pig profundus tendon stored at room temperature at different postmortem time intervals

Mollerup et al. in FEMS Microbiology Letters
Rapid in vivo development of resistance to daptomycin in vancomycin-resistant Enterococcus faecium due to genomic alterations

Kohler et al. in npj Breast Cancer
Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

Li et al. in Protein Science
PcoB is a defense outer membrane protein that facilitates cellular uptake of copper

Caliandro et al. in Free Radical Biology and Medicine
A redox-dependent thiol-switch and a Ca2+ binding site within the hinge region hierarchically depend on each other in α7β1 integrin regulation

Hempel et al. in The Journal of Infectious Diseases
Specific components associated with the endothelial glycocalyx are lost from brain capillaries in cerebral malaria

Dos Santos et al. in Cellular and Molecular Life Sciences
Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

Allahghadry et al. in Journal of Applied Microbiology
Clarification of large-volume bacterial cultures using a centrifuge-free protocol

Montagna et al. in Cell Death & Disease
Autophagy guards tendon homeostasis

Holm et al. in Proceedings of the National Academy of Sciences
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio

Chaaban et al. in The Journal of Physical Chemistry Letters
Ion-Mediated Morphological Diversity in Protein Amyloid Systems

Yeung et al. in Science Advances
Circadian regulation of protein cargo in extracellular vesicles

Khare et al. in Atherosclerosis
In vivo detection of urokinase-type plasminogen activator receptor (uPAR) expression in arterial atherogenesis using [64Cu]Cu-DOTA-AE105 positron emission tomography (PET)

Münter et al. in Acta Biomaterialia
Mechanisms of Selective Monocyte Targeting by Liposomes Functionalized with a Cationic, Arginine-Rich Lipopeptide

Rosina et al. in Cell Metabolism
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue

Goldhammer et al. in Communications Biology
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation

Andersen et al. in The Journal of Clinical Investigation
Coding variants identified in patients with diabetes alter PCIK1 BAR domain function in insulin granule biogenesis

Leal-Dutra et al. in bioRxiv
A domesticated fungal cultivar recycles its cytoplasmic contents as nutritional rewards for its leafcutter ant farmers

Soendenbroe et al. in The Journal of Physiology
Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

Bhattarai et al. in Research Square
Solubility of spruce galactoglucomannans determines interfacial morphology and emulsion stability

Fernström, J. from Lund University, Faculty of Medicine
Mitochondrial Biology, Cellular Stress and Inflammation in Depression and Suicidality

Barington et al. in Cells
GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity

Wang et al. in Food Hydrocolloids
Differences in physicochemical properties of high-moisture extrudates prepared from soy and pea protein isolates

Basak et al. in Nanoscale Advances
Nanoconfined anti-oxidizing RAFT nitroxide radical polymer for reduction of low-density lipoprotein oxidation and foam cell formation

 

 

Rømer et al. in British Journal of Cancer
Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin

Sandoval-Ibáñez et al. in Proc Natl Acad Sci U S A
Curvature thylakoid 1 proteins modulate prolamellar body morphology and promote organized thylakoid biogenesis in Arabidopsis thaliana

Pettygrove et al. in Biomaterials
Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

Jensen et al. in Journal of Visualized Experiments
Quantification of Subcellular Glycogen Distribution in Skeletal Muscle Fibers using Transmission Electron Microscopy

Martinez-Val et al. in Nature Communications
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

Van der Horst et al. in Physiological Reports
Functional sympatholysis in mouse skeletal muscle involves sarcoplasmic reticulum swelling in arterial smooth muscle cells

Dall et al. in Journal of Biological Chemistry
Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis–like phenotypes

Hawez et al. in Laboratory Investigation
c-Abl kinase regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis

Frørup et al. in Frontiers in Immunology
Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of MiRNAs During the Postpartum Period

Prause et al. in International Journal of Molecular Sciences
Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction

Tamáš et al. in Physiological Reports
Mutual stimulatory signaling between human myogenic cells and rat cerebellar neurons

Svensson et al. in Journal of the Mechanical Behavior of Biomedical Materials
Mechanical properties of human patellar tendon collagen fibrils. An exploratory study of aging and sex

Heilmann et al. in STAR Protocols
Quantifying spatial position in a branched structure in immunostained mouse tissue sections

Ruth et al. in Nature
Genetic insights into biological mechanisms governing human ovarian ageing

Correll et al. in Translational Vision Science & Technology
In Vivo Labeling and Tracking of Proliferating Corneal Endothelial Cells by 5-Ethynyl-2′-Deoxyuridine in Rabbits

Abraham et al. in Journal of Biological Chemistry
Collagen’s primary structure determines collagen:HSP47 complex stoichiometry

Rønnov-Jessen et al. in Scientific Reports
Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen

Mariani et al. in Nature Communications
A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm

Saljic et al. in IJC Heart & Vasculature
Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation

Tozzi et al. in The Journal of Physiology
Dynamic interplay between AfadinS1795 phosphorylation and diet regulates glucose homeostasis in obese mice

Bor et al. in Journal of Colloid and Interface Science
Cell medium-dependent dynamic modulation of size and structural transformations of binary phospholipid/ω-3 fatty acid liquid crystalline nano-self-assemblies: implications in interpretation of cell uptake studies

Fuentes-Lemus et al. in Food Hydrocolloids
High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

Carabias et al. in Nature Communications
Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3

Nüchel et al. in Molecular Cell
An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

Marinova et al. in STAR Protocols
Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models

Kostrikov et al. in Communications Biology
Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

Zambach et al. in PNAS
Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

Hawez et al. in Journal of Leukocyte Biology
MiR-155 regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis

Basse et al. in Molecular Metabolism
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

Allodi et al. in Nature Communications
Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

Dahl et al. in Interventional Neuroradiology
Polytetrafluoroethylene coating fragments during neuroendovascular therapy: An analysis of two damaged microguidewires

Ferrari at Lund University
Genetic Screening in Patients Suspected of Inherited Bleeding Disorders

Lund et al. in bioRxiv
Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

Khumpirapang et al. in European Journal of Pharmaceutics and Biopharmaceutics
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

Kristensson in Cells
The Game of Tubulins

de Guia et al. in The FASEB Journal
Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting‐ and ghrelin‐mediated food intake

Webb et al. in Scientific Reports
Detection of biological signals from a live mammalian muscle using an early stage diamond quantum sensor

Missel et al. in Current Research in Structural Biology
Cyclohexyl-α maltoside as a highly efficient tool for membrane protein studies

Dabelsteen et al. in Developmental Cell
Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

Jensen et al. in Experimental Physiology
Glycogen supercompensation is due to increased number, not size, of glycogen particles in human skeletal muscle

Knudsen et al. in Translational Sports Medicine
No demonstrable ultrastructural adaptation of the human myotendinous junction to immobilization or 4 weeks of heavy resistance training

Gudbergsson at Aalborg Universitetsforlag
Understanding Glioblastoma Stem-Like Cells in Quest of a Target to Direct Treatment

Bennet-Lenane et al. in European Journal of Pharmaceutical Sciences
Exploring porcine gastric and intestinal fluids using microscopic and solubility estimates: Impact of placebo self-emulsifying drug delivery system administration to inform bio-predictive in vitro tools

Somyajit et al. in Developmental Cell
Homology-directed repair protects the replicating genome from metabolic assaults

Lauscke et al. in Stem Cells and Development
A comparative assessment of marker expression between cardiomyocyte differentiation of human induced pluripotent stem cells and the developing pig heart

Liu et al. in BioRxiv
Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

Górecki et al. in Langmuir
Effect of Detergents on Morphology, Size Distribution, and Concentration of Copolymer-Based Polymersomes

Galparsoro et al. in ACS Applied Bio Materials
Conformational Transitions upon Maturation Rule Surface and pH-Responsiveness of α-Lactalbumin Microparticulates

Mund et al. in BioRxiv
AI-driven Deep Visual Proteomics defines cell identity and heterogeneity

Grevengoed et al. in The Journal of Clinical Investigation
An abundant biliary fatty acid metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides

Linders et al. in European Surgical Research
Complement Component 3 Is Required for Tissue Damage, Neutrophil Infiltration, and Ensuring NET Formation in Acute Pancreatitis

Adams et al. in Journal of Experimental Medicine
Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria

Vadivel et al. in Cancers
JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL)

 

 

Alhede et al. in Pathogens and Disease
The origin of extracellular DNA in bacterial biofilm infections in vivo

Andersen et al. in Endocrinology
Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

Jakobsen et al. in Translational Sports Medicine
Adipocytes are present at human and murine myotendinous junctions

Bechmann et al. in Oncotarget
Heterogeneity of CEACAM5 in breast cancer

Yeung et al. in Cell Communication and Signalling
Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

Santiveri et al. in Cell
Structure and Function of Stator Units of the Bacterial Flagellar Motor

Bloch et al. in Methods in Molecular Biology
Membrane Protein Cryo-EM: Cryo-Grid Optimization and Data Collection with Protein in Detergent

Molina et al. in Current Opinion in Structural Biology
Structural basis of CRISPR-Cas Type III prokaryotic defence systems

Paul et al. in Biomedical Journal
CRISPR-Cas12a: Functional overview and applications

Small et al. in The Journal of Physiology
Contraction influences Per2 gene expression in skeletal muscle through a calcium‐dependent pathway

Stella et al. in Cell
Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

Molina et al. in Nature Communications
Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

Sofos et al. in Molecular Cell
Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

Bundgaard et al. in Journal of Experimental Biology
Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia

Skaaning et al. in Biomolecules
The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin

Fougeoux et al. in Nature Research
Capsid-like particles decorated with the SARS2-CoV-2 receptor-binding domain elicit strong virus neutralization activity

Pounot et al. in The Journal of Physical Chemistry Letters
Tracking Internal and Global Diffusive Dynamics During Protein Aggregation by High-Resolution Neutron Spectroscopy

Seymour et al. in Developmental Cell
Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

Kim et al. in Journal of Histochemistry & Cytochemistry
The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells

Bohr et al. in Acta Biometrialia
Antioxidant-mediated control of degradation and drug release from surface-eroding poly(ethylene carbonate)

Cruz et al. in Scientific Reports
Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Mellergaard et al. in Journal of Biological Chemistry
Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes

Fredericia et al. in International Journal of Radiation Biology
Cs-131 as an experimental tool for the investigation and quantification of the radiotoxicity of intracellular Auger decays in vitro

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